{"id":32669,"date":"2024-06-28T12:51:45","date_gmt":"2024-06-28T16:51:45","guid":{"rendered":"https:\/\/genomecanada.ca\/?p=32669"},"modified":"2024-07-25T16:05:36","modified_gmt":"2024-07-25T20:05:36","slug":"la-genomique-au-service-de-la-decouverte-de-medicaments-a-partir-de-champignons","status":"publish","type":"post","link":"https:\/\/genomecanada.ca\/fr\/la-genomique-au-service-de-la-decouverte-de-medicaments-a-partir-de-champignons\/","title":{"rendered":"La g\u00e9nomique au service de la d\u00e9couverte de m\u00e9dicaments \u00e0 partir de champignons"},"content":{"rendered":"\t\t
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Les champignons pourraient jouer un r\u00f4le cl\u00e9 dans la d\u00e9couverte de m\u00e9dicaments \n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Les champignons ont jou\u00e9 un r\u00f4le cl\u00e9 dans le d\u00e9veloppement de nombreux m\u00e9dicaments, comme la p\u00e9nicilline, mais la production des ingr\u00e9dients m\u00e9dicinaux actifs \u00e0 grande \u00e9chelle \u00e0 des fins de R-D s\u2019est av\u00e9r\u00e9e un d\u00e9fi de taille pour faire avancer la d\u00e9couverte de m\u00e9dicaments fongiques.<\/p>

Une plateforme de biologie synth\u00e9tique pour soutenir la d\u00e9couverte de m\u00e9dicaments fongiques<\/a> cr\u00e9era une plateforme biologique synth\u00e9tique souple, \u00e9volutive et rentable qui soutient la synth\u00e8se de mol\u00e9cules fongiques diversifi\u00e9es et produit un compos\u00e9 suffisant. Dirig\u00e9e par Gerard Wright de la McMaster University, elle tirera parti de la plateforme exclusive de d\u00e9couverte de m\u00e9dicaments soutenue par l\u2019IA de Kapoose Creek Bio (KCB), appel\u00e9e unEarth Rx, qui exploite la nature pour explorer de nouvelles pistes de m\u00e9dicaments th\u00e9rapeutiques.<\/p>

Gr\u00e2ce \u00e0 un financement de plus de 2,3 M$ annonc\u00e9 en mai 2024 dans le cadre d\u2019un investissement plus important de 41 M$<\/a>, la plateforme utilisera des solutions de g\u00e9nomique et de m\u00e9tabolomique pour mettre au point un syst\u00e8me d\u2019expression biosynth\u00e9tique pour les compos\u00e9s fongiques cod\u00e9s g\u00e9n\u00e9tiquement.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Photo de l\u2019\u00e9quipe du projet. De gauche \u00e0 droite : Gerry Wright, Eric Brown, Divya Panchal.<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Pour en savoir plus sur cet investissement dans la recherche-d\u00e9veloppement en g\u00e9nomique, cliquez ici.<\/a><\/em><\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\u00c0 PROPOS DU PPAG<\/span><\/h3>

Le Programme de partenariats pour les applications de la g\u00e9nomique<\/a> (PPAG) finance des projets de recherche r\u00e9alis\u00e9s en partenariat avec l\u2019industrie pour r\u00e9soudre des probl\u00e8mes concrets.<\/strong> Con\u00e7u pour acc\u00e9l\u00e9rer les r\u00e9percussions sociales et \u00e9conomiques de la g\u00e9nomique, le PPAG ouvre la voie \u00e0 la recherche, \u00e0 l\u2019innovation et \u00e0 l\u2019application pour prosp\u00e9rer de mani\u00e8re concert\u00e9e. Les projets de PPAG s\u2019attaquent \u00e0 des probl\u00e8mes et saisissent des possibilit\u00e9s concr\u00e8tes par une collaboration accrue entre les chercheurs en g\u00e9nomique et les utilisateurs de leurs travaux. Ils visent \u00e0 stimuler les investissements des secteurs public et priv\u00e9 dans les technologies canadiennes de la g\u00e9nomique, \u00e0 faire avancer ces technologies aux derniers stades de leur mise au point et \u00e0 faire progresser l\u2019adoption de ces derni\u00e8res par les r\u00e9cepteurs.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Les champignons pourraient jouer un r\u00f4le cl\u00e9 dans la d\u00e9couverte de m\u00e9dicaments Les champignons ont jou\u00e9 un r\u00f4le cl\u00e9 dans le d\u00e9veloppement de nombreux m\u00e9dicaments, comme la p\u00e9nicilline, mais la production des ingr\u00e9dients m\u00e9dicinaux actifs \u00e0 grande \u00e9chelle \u00e0 des fins de R-D s\u2019est av\u00e9r\u00e9e un d\u00e9fi de taille pour faire avancer la d\u00e9couverte de […]<\/p>\n","protected":false},"author":8,"featured_media":32292,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[127,85,149],"tags":[],"mission-categories":[161],"class_list":["post-32669","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news-fr","category-non-classifiee","category-featured-fr","mission-categories-agriculture-and-food-fr"],"acf":[],"yoast_head":"\nLa g\u00e9nomique au service de la d\u00e9couverte de m\u00e9dicaments \u00e0 partir de champignons - 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