{"id":32716,"date":"2024-07-04T11:58:22","date_gmt":"2024-07-04T15:58:22","guid":{"rendered":"https:\/\/genomecanada.ca\/?p=32716"},"modified":"2024-07-04T14:05:57","modified_gmt":"2024-07-04T18:05:57","slug":"la-genomique-au-service-de-lamelioration-des-resultats-de-la-fiv","status":"publish","type":"post","link":"https:\/\/genomecanada.ca\/fr\/la-genomique-au-service-de-lamelioration-des-resultats-de-la-fiv\/","title":{"rendered":"La g\u00e9nomique au service de l\u2019am\u00e9lioration des r\u00e9sultats de la FIV"},"content":{"rendered":"\t\t
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Am\u00e9liorer les r\u00e9sultats et faciliter l\u2019acc\u00e8s pour les futures familles canadiennes\n\n\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Chaque ann\u00e9e, environ quatre millions de personnes ont recours \u00e0 la f\u00e9condation in vitro (FIV), mais seulement 34 % des cycles de FIV r\u00e9ussissent. La g\u00e9n\u00e9tique de l\u2019embryon lui-m\u00eame entra\u00eene dans au moins 85 % des cas, le taux \u00e9lev\u00e9 d\u2019\u00e9chec en ce qui concerne l\u2019implantation des embryons transf\u00e9r\u00e9s et les grossesses \u00e0 terme. Malgr\u00e9 le co\u00fbt, soit environ 20 000 $ par cycle, les cliniciens ne disposent actuellement pas de la technologie n\u00e9cessaire pour r\u00e9aliser des tests g\u00e9n\u00e9tiques complets sur les embryons.<\/p>

Un nouveau projet, dirig\u00e9 par Jeremy Grushcow de Juniper Genomics et de la Dre Sophie Petropoulos de l\u2019Universit\u00e9 de Montr\u00e9al, vise \u00e0 \u00e9laborer un test g\u00e9n\u00e9tique complet de s\u00e9quen\u00e7age du g\u00e9nome entier \u00e0 partir d\u2019une seule cellule pour les embryons afin de donner aux patientes et aux cliniciens de la FIV autant de certitude que possible que le premier embryon qu\u2019ils d\u00e9cident de transf\u00e9rer sera une r\u00e9ussite.<\/p>

Le projet, intitul\u00e9 S\u00e9quen\u00e7age du g\u00e9nome entier de l\u2019embryon en vue d\u2019am\u00e9liorer les r\u00e9sultats de la FIV<\/a>, et dirig\u00e9 en partenariat avec Juniper Genomics, d\u00e9veloppera un flux de travail \u00e9volutif pour l\u2019analyse des biopsies par la manipulation des cellules et la pr\u00e9paration d\u2019\u00e9chantillons donnant des r\u00e9sultats de s\u00e9quen\u00e7age optimaux de mani\u00e8re rentable. Avec pr\u00e8s de 5,7 M$, annonc\u00e9s en mai dans le cadre d\u2019un investissement plus important de 41 M$<\/a>, le projet a le potentiel de transformer la FIV \u2013 en am\u00e9liorant les r\u00e9sultats et en facilitant l\u2019acc\u00e8s pour les patientes canadiennes.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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De gauche \u00e0 droite : Les membres de l\u2019\u00e9quipe du projet Savana Biondic, le Dr Jeremy Grushcow et le Dr G. Adam Reeves devant une image microscopique d\u2019un embryon de recherche donn\u00e9<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Pour en savoir plus sur cet investissement dans la recherche-d\u00e9veloppement en g\u00e9nomique, cliquez ici<\/a>.<\/em><\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\u00c0 PROPOS DU PPAG<\/span><\/h3>

Le Programme de partenariats pour les applications de la g\u00e9nomique<\/a> (PPAG) finance des projets de recherche r\u00e9alis\u00e9s en partenariat avec l\u2019industrie pour r\u00e9soudre des probl\u00e8mes concrets.<\/strong> Con\u00e7u pour acc\u00e9l\u00e9rer les r\u00e9percussions sociales et \u00e9conomiques de la g\u00e9nomique, le PPAG ouvre la voie \u00e0 la recherche, \u00e0 l\u2019innovation et \u00e0 l\u2019application pour prosp\u00e9rer de mani\u00e8re concert\u00e9e. Les projets de PPAG s\u2019attaquent \u00e0 des probl\u00e8mes et saisissent des possibilit\u00e9s concr\u00e8tes par une collaboration accrue entre les chercheurs en g\u00e9nomique et les utilisateurs de leurs travaux. Ils visent \u00e0 stimuler les investissements des secteurs public et priv\u00e9 dans les technologies canadiennes de la g\u00e9nomique, \u00e0 faire avancer ces technologies aux derniers stades de leur mise au point et \u00e0 faire progresser l\u2019adoption de ces derni\u00e8res par les r\u00e9cepteurs.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Am\u00e9liorer les r\u00e9sultats et faciliter l\u2019acc\u00e8s pour les futures familles canadiennes Chaque ann\u00e9e, environ quatre millions de personnes ont recours \u00e0 la f\u00e9condation in vitro (FIV), mais seulement 34 % des cycles de FIV r\u00e9ussissent. La g\u00e9n\u00e9tique de l\u2019embryon lui-m\u00eame entra\u00eene dans au moins 85 % des cas, le taux \u00e9lev\u00e9 d\u2019\u00e9chec en ce qui […]<\/p>\n","protected":false},"author":8,"featured_media":32362,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[127,85,149],"tags":[],"mission-categories":[160],"class_list":["post-32716","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news-fr","category-non-classifiee","category-featured-fr","mission-categories-sante"],"acf":[],"yoast_head":"\nLa g\u00e9nomique au service de l\u2019am\u00e9lioration des r\u00e9sultats de la FIV - GenomeCanada<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/genomecanada.ca\/fr\/la-genomique-au-service-de-lamelioration-des-resultats-de-la-fiv\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"La g\u00e9nomique au service de l\u2019am\u00e9lioration des r\u00e9sultats de la FIV - GenomeCanada\" \/>\n<meta property=\"og:description\" content=\"Am\u00e9liorer les r\u00e9sultats et faciliter l\u2019acc\u00e8s pour les futures familles canadiennes Chaque ann\u00e9e, environ quatre millions de personnes ont recours \u00e0 la f\u00e9condation in vitro (FIV), mais seulement 34 % des cycles de FIV r\u00e9ussissent. 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