Compr\u00e9hension de la cause des maladies g\u00e9n\u00e9tiques. Un Canadien sur douze est atteint d\u2019une \u00ab maladie orpheline \u00bb. La d\u00e9couverte d\u2019un traitement efficace de ces maladies est souvent compliqu\u00e9e par une compr\u00e9hension scientifique insuffisante de la maladie, l\u2019attribution limit\u00e9e des ressources \u00e0 l\u2019\u00e9tude de ces derni\u00e8res et le co\u00fbt de la mise au point de nouveaux m\u00e9dicaments. M\u00eame si, individuellement, elles sont rares, ces maladies ont un effet cumulatif socio\u00e9conomique et sanitaire sur trois millions de Canadiens. La d\u00e9couverte de g\u00e8nes offre maintenant un nouvel espoir de nouvelles th\u00e9rapies. Misant sur le succ\u00e8s remport\u00e9 par l\u2019Initiative de g\u00e9n\u00e9tique m\u00e9dicale et de g\u00e9nomique de la r\u00e9gion de l\u2019Atlantique, des chercheurs mettent au point de nouvelles th\u00e9rapies pour les patients atteints de maladies orphelines, en moins de temps et \u00e0 moindre co\u00fbt.<\/p>\n
Gr\u00e2ce au financement de G\u00e9nome Canada, des chercheurs s\u2019emploient \u00e0 d\u00e9couvrir les g\u00e8nes responsables de ces maladies, \u00e0 trouver des cibles th\u00e9rapeutiques et \u00e0 identifier de petites mol\u00e9cules et pistes pour la mise au point de m\u00e9dicaments qui pourraient att\u00e9nuer l\u2019impact de ces maladies. Les chercheurs se concentrent \u00e9galement sur l\u2019utilisation ou la conversion de m\u00e9dicaments existants afin de r\u00e9pondre plus rapidement \u00e0 des besoins m\u00e9dicaux qui demeurent irr\u00e9solus.<\/p>\n
Dans le cadre de leurs travaux, les chercheurs examinent les enjeux \u00e9thiques auxquels font face les patients atteints de maladies orphelines, y compris l\u2019\u00e9valuation de mod\u00e8les r\u00e9glementaires internationaux pour les m\u00e9dicaments orphelins et les besoins des patients individuels.<\/p>\n","protected":false},"excerpt":{"rendered":"
Compr\u00e9hension de la cause des maladies g\u00e9n\u00e9tiques. Un Canadien sur douze est atteint d\u2019une \u00ab maladie orpheline \u00bb. La d\u00e9couverte d\u2019un traitement efficace de ces maladies est souvent compliqu\u00e9e par une compr\u00e9hension scientifique insuffisante de la maladie, l\u2019attribution limit\u00e9e des ressources \u00e0 l\u2019\u00e9tude de ces derni\u00e8res et le co\u00fbt de la mise au point de […]<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"project-categories":[93],"genome-competitions":[225],"project-sector":[],"genome_centres":[109],"class_list":["post-10581","project","type-project","status-publish","hentry","project-categories-large-scale-science-fr","genome-competitions-concours-2010-projets-de-recherche-appliquee-a-grande-echelle-volet-multisectoriel","genome_centres-genome-atlantic-fr"],"acf":[],"yoast_head":"\n