New pan-Canadian All for One initiative will increase equitable access to genome-wide sequencing for diagnosis and treatment of genetic disease.
The Genome Canada-led All for One precision health partnership launched today will advance a new standard of health care for Canadians, expanding access to genome-wide sequencing for diagnosis and treatment of life-threatening genetic diseases.
The $39 million All for One initiative includes $13 million in federal investment through Genome Canada and $26 million in co-funding from industry, health-care organizations, provincial and other partners brought in through six regional Genome Centres.
Advances in precision health—which harnesses the power of genome sequencing to diagnose and inform treatment of genetic conditions—are revolutionizing healthcare, but access to clinical genomic testing across Canada remains inconsistent.
With pan-Canadian reach and strong partnership from provincial and regional health services authorities, All for One will be a core building block of a coordinated human health genomics ecosystem in Canada, bridging clinical care and cutting-edge research. A foundational element of Genome Canada’s precision health leadership, All for One will also make a major contribution to Canada’s national rare disease strategy.
All for One is:
- Now deployed across six implementation projects serving nine provinces, funded through the Genomic Applications Partnership Program (GAPP).
- Unified by the All for One Policy Toolkit, to ensure ethical, equitable collection of genomic and clinical data.
- Bolstered by the development of a Pan-Canadian Health Data Ecosystem, which will connect and leverage genomic and clinically generated data to improve patient care and fuel life saving scientific breakthroughs.
The launch of All for One follows the announcement last month of the final project in the initiative, funded through Ontario Genomics. This project will pilot an optimized clinical genome-wide sequencing service for patients with rare diseases in Ontario, delivered by CHEO and the Hospital for Sick Children (SickKids) in collaboration with the Ontario Ministry of Health. Currently, more than one third of Ontarians with a rare disease lack a genetic diagnosis, despite lengthy and costly investigations.
Explore All for One projects below.
“Our government is ensuring that Canada is a leading force in the science of genomics because we know the positive impacts that will have on our healthcare systems. Through our investment in Genome Canada’s All for One initiative, we are leading the way and supporting partnerships to build a stronger system with more precise healthcare for all Canadians.”
– The Honourable François-Philippe Champagne, Minister of Innovation, Science and Industry
“Genomics-enabled precision health is a game-changer for patient care in Canada. The All for One precision health initiative will be a key pillar in a coordinated human health genomics ecosystem for Canadians. Genome Canada is proud to support this pan-Canadian collaboration, helping establish a new standard of care for patients with serious genetic disease, bringing the power of genomics into the doctor’s office and enabling life-saving research through genomic and clinical data sharing.”
– Dr. Rob Annan, President and CEO, Genome Canada
“Access to state-of-the-art genome-wide sequencing will be life-saving and transformative for Canadian patients, some of whom have been struggling for years to get a diagnosis. All for One opens the door for appropriate care and also opportunity for clinical trials and other interventions. Kudos to Genome Canada and all of the partners for continuing to put patients first.”
– Dr. Durhane Wong-Rieger, President & CEO, Canadian Organization for Rare Disorders
Learn more about the All for One-related projects
- British Columbia: Implementation of Diagnostic Whole Genome Sequencing for Rare Diseases in British Columbia
- Alberta: TIGeR: Translational Implementation of Genomics for Rare diseases
- Prairies: Canadian Prairie Metabolic Network
- Ontario: Optimization and Implementation of a Clinical Genome-Wide Sequencing Service for Rare Disease Diagnosis in Ontario
- Quebec: Rapid Whole-Genome Sequencing in Acute Care Neonates and Infants
- Atlantic Canada: Implementation of Clinical Exomes in a Pre- and Peri-Natal Setting
- Data policy: All for One Policy Toolkit
- Health data ecosystem: Defining a Canadian Data Solution That Will Deliver Precision Health for Rare Genetic Disease
- Backgrounder: All for One: New pan-Canadian initiative will increase equitable access to genome-wide sequencing for diagnosis and treatment of genetic disease
- Web page: Genome Canada’s All for One initiative
About Genome Canada
Genome Canada is a national not-for-profit organization addressing Canada’s greatest challenges and opportunities through research and innovation in genomics and associated biosciences. With a 21-year track record of impact across sectors, a pan-Canadian network of six regional Genome Centres, and strong partnerships across the public, private, non-profit and academic sectors at home and internationally, we translate research into real-world impact in health, climate action and food security.