Next Generation Bioinformatics for Clinical Genomics: using de novo assembly in personalized medicine

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Outcome

Status

Past

Competition

None

Genome Centre(s)

GE3LS

No

Project Leader(s)

Inanc Birol

Fiscal Year Project Launched

2013-2014

Project Description

Genomics technologies that detect variations and mutations in DNA and RNA can advance cancer care and reduce healthcare costs by improving preventive care, diagnosis and treatment. Advanced high throughput DNA and RNA sequencing technologies can help realize this vision by generating large amounts of sequence data rapidly and at low cost. However, solid analysis of the generated data is essential to reach its full potential and will provide the backbone to application.

Drs. Inanc Birol, Steven Jones and Aly Karsan are developing an analytical approach to detect variations and mutations in DNA and RNA related to cancer diagnosis and care. This approach could lead to more efficient and effective clinical testing for various types of cancers across Canada.

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