Personalized Medicine Strategies for Molecular Diagnostics and Targeted Therapeutics of Cardiovascular Diseases

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Outcome

Status

Active

Competition

None

Genome Centre(s)

GE3LS

No

Project Leader(s)

Jean-Claude Tardif

Fiscal Year Project Launched

2012-2013

Project Description

Cardiovascular disease is the leading cause of death and hospitalization in the world. In  Canada 80,000 people died in 2010 of cardiovascular disease, which accounts for 35  per cent of all deaths in the country. Currently, 1.3 million Canadians suffer from  cardiovascular disease, causing a serious economic burden. The cost is estimated to  $22.2 billion per year, which constitutes the highest direct healthcare costs.

The team led by Drs. Jean­Claude Tardif and Marie­Pierre Dubé are applying their  expertise in how genes influence drug efficacy and toxicity to provide guidance to health  professionals in the selection and dosing of a specific drug. This will improve patient  care, reduce harmful side effects and lower health care costs by reducing the use of  ineffective drugs and unnecessary spending by healthcare payers.

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